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【Exclusive】Recommended Series | Resorufin: The Fluorescent Probe Illuminating the Microscopic World
2024/12/13 11:24:46 Browse volume(59)In scientific research, precise and sensitive tools are essential for obtaining reliable results. Today, we introduce to you a widely used fluorescent dye—Resorufin. Resorufin is renowned for its superior fluorescence properties and stability, making it an indispensable tool in biochemistry, environmental monitoring, and medical research. It is not only suitable for enzyme activity detection and cell imaging in the laboratory but also for analysis in environmental and food safety, aiding researchers and professionals in more effective monitoring and evaluation.
Resorufin is a special fluorescent dye that emits intense pink fluorescence under specific conditions. This fluorescence is highly stable and resistant to external factors. The 7-hydroxyphenyl group in the Resorufin molecule can be chemically modified to be quenched, resulting in minimal fluorescence in its initial state. Only when it interacts with a specific target substance does the quenched 7-hydroxyphenyl group get released or restored, producing a bright fluorescent signal. This "light switch" characteristic makes Resorufin an ideal optical probe, enhancing detection sensitivity and specificity while broadening its applicability across various fields.
High Sensitivity: Resorufin can detect extremely low concentrations of target substances, making it suitable for trace analysis.
Good Specificity: Its selective reaction with specific target substances reduces background interference and improves detection accuracy.
Wide Application Range: From measuring enzyme activity and ion concentration to tracking reactive oxygen species (ROS) within cells, Resorufin can be applied to almost any research area requiring fluorescent labeling.
Excellent Biocompatibility: Good cell membrane permeability and dispersibility make it ideal for live cell imaging and in vivo analysis.
Ease of Use: Simple chemical reactions can activate the fluorescent signal, simplifying experimental procedures.
Biological Research: Used for labeling cellular microfilaments and assessing cell viability, providing direct fluorescent readings.
Cell Imaging: Reacts with specific enzymes or molecules to emit highly selective and sensitive fluorescent signals, suitable for imaging studies such as melanoma cells.
Environmental Protection: Aids in detecting harmful substances in water bodies and other environments, ensuring the safety of our living environment.
Food Safety: Detects residual additives in food, such as benzoyl peroxide in flour, ensuring food safety.
Reactive Oxygen Species Monitoring: Through fluorescence assays, detects intracellular hydrogen peroxide (H?O?) and other ROS, studying cellular oxidative stress.
While Resorufin and its derivatives possess excellent fluorescent properties, their synthesis and purification have historically been challenging, leading to high prices and limiting their applications. Geneseqtools Biotech has overcome these technical challenges, enabling the stable supply of high-quality and affordable Resorufin and its derivatives to the market.
Below is a selection of innovative products developed by Geneseqtools based on Resorufin:
CAS Number： 635-78-9
Chinese Name： 試鹵靈
Another Name： 7-Hydroxy-3H-phenoxazin-3-one
Product Packaging：mg級(jí)~kg級(jí)
Application： Enzyme substrate
Product Code： R01010001
CAS Number： 95079-19-9
Chinese Name： 試鹵靈-β-D-半乳糖苷
Another Name： Resorufin-Gal
Product Packaging：Available in mg to kg quantities
Application： Enzyme substrate
Product Code： R02010001
CAS Number： 5725-91-7
Chinese Name： 乙基試鹵靈
Another Name： Resorufin Ethyl Ether
Product Packaging： Available in mg to kg quantities
Application： Enzyme substrate
Product Code： R03010001
CAS Number： 5725-89-3
Chinese Name： 甲基試鹵靈
Another Name：Resorufin Methyl Ether
Product Packaging： Available in mg to kg quantities
Application： Enzyme substrate
Product Code： R03010002
CAS Number： 87687-03-4
Chinese Name： 試鹵靈戊醚
Another Name： Resorufin Pentyl Ether
Product Packaging： Available in mg to kg quantities
Application： Enzyme substrate
Product Code： R03010003
CAS Number： 87687-02-3
Chinese Name： 芐基試鹵靈
Another Name： Resorufin Benzyl Ether
Product Packaging： Available in mg to kg quantities
Application： Enzyme substrate
Product Code： R03010004
Founded in 2015, the company focuses on the research, development, production, and sales of biochemical reagents for microbial detection, gene sequencing, and in vitro molecular diagnostics. We are committed to providing high-quality biochemical reagents and professional custom synthesis services. Our product range covers over a dozen categories with nearly a thousand innovative products. Adhering to the core values of "Customer First, Integrity, and Professionalism," we strive to meet the diverse needs of our clients in research and testing.
WeChat Office Account：Geneseqtools Biotech
Geneseqtools Website：http://m.dg99.com.cn
Consultation Hotline：+86-0755-36820717
QQ：2370561481
Email：sales@geneseqtools.com
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